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These are worms.

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Not the kind of worms
you find crawling in the dirt.

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These are parasitic roundworms.

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They live inside
a human being's intestines.

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Each of these worms can grow
up to 12 inches long,

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and there are 200 of them
in this jar for a reason,

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because that is the number
you might typically find

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in the belly of a single infected child.

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Worm infections have been around
for thousands of years.

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They have influenced the outcomes of wars,

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and they have long stymied human health.

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Roundworm, hookworm,

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whipworm, schistosomiasis:

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infections from these species
cause pain and discomfort.

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They steal nutrients and zap energy.

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They both physical and cognitive growth.

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In most cases, these worms
may not be fatal,

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but paradoxically,
that's part of the problem.

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It means that many countries
simply have not been able

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to prioritize their treatment.

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There's a social cost to that:

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children without access
to deworming treatments

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have lower rates of school attendants.

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Adults who grow up
without deworming medicine

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are less productive
and have lower lifelong earnings.

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What intestinal worms do, really,

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is limit potential.

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Currently, there are 1.7 billion people
in the world still at risk for worms.

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Six hundred million of them are in Africa.

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For every dollar invested
in worm control and prevention,

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African countries see up to
42 dollars return in economic benefits.

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The good news is that deworming
treatment is extremely easy.

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One to three pills
given once or twice a year

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is enough to take a child
from 200 worms to zero

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and to protect them
from infection going forward.

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In communities where
there's a high prevalence of worms,

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treatment can be done right at school.

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This process is extremely simple and fast.

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In Ethiopia, for example,
this is done for 20 million children

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in a matter of weeks.

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The world has come a long way
on getting deworming medicines

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to the people who need them,

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and African governments want
to gain more traction.

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It's now time to match their ambition.

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The END Fund will work with governments

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to create a plan that drastically reduces
the burden of disease caused by worms.

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They will work together to ensure
prevention and treatment programs

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can serve everyone.

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The END Fund has an audacious idea:

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they believe we are the generation to end
sickness from worm infections forever.

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The key is not simply to build
new programs from scratch,

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but to amplify the efforts of the programs
that are already taking shape.

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By examining the problem
of how worms transmit disease,

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the END Fund has identified five key areas
where they can drive improvement.

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Number one: lower the cost of treatment.

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Many pharmaceutical companies
offer deworming medicines for free,

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so the END Fund works
with the right partners

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to coordinate their delivery.

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They will continue
to secure drug donations

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for additional at risk populations.

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They can now do it for less than
25 cents per child per year.

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Number two: focus on prevention.

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The END Fund calls in the right partners
to educate communities

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on sanitation and hygiene

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in order to change behaviors
around things like hand-washing

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and latrine use,

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ensuring people are not
continually reinfected.

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Number three: invest in innovation.

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The END Fund has contributed to deworming

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by introducing innovative techniques
that effectively target and treat people.

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They will test new delivery methods,

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target the environments
where parasites thrive,

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and influence behavior change.

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Number four: monitor and evaluate.

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The END Fund collects detailed data
on all programs on a regular basis

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to help them get better
and better over time.

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Number five: increase local ownership.

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At all stages of the process,

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the END Fund works with government
and local stakeholders

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to encourage co-financing commitments
that supports deworming efforts.

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They also worked with
African philanthropists

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and corporate leaders
to partner on these efforts.

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There's an incredible opportunity
to work together to create a new system

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for disease elimination
for the next decade and beyond.

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Part of the money the END Fund needs

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will go directly toward delivering
deworming treatments

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to communities that need it,

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and part will go towards facilitating
the handover of programs

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to local ownership.

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Together, these efforts will create
prevention and treatment programs

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that are sustainable far into the future.

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If this plan gets fully funded
for the next six years,

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tens of millions of people
will receive deworming treatment.

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With that, countries will be interrupting
the cycle of disease transmission

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at all levels,

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and, most importantly, people
will experience significant improvements

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in their mental, physical,
and social health.

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Just imagine the potential
that will be gained

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when people can stop
worrying about these

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and can put their energy
to things like these.