WEBVTT 00:00:00.722 --> 00:00:02.289 These are worms. 00:00:02.289 --> 00:00:04.968 Not the kind of worms you find crawling in the dirt. 00:00:04.968 --> 00:00:07.077 These are parasitic roundworms. 00:00:07.077 --> 00:00:09.536 They live inside a human being's intestines. 00:00:09.536 --> 00:00:12.348 Each of these worms can grow up to 12 inches long, 00:00:12.348 --> 00:00:14.702 and there are 200 of them in this jar for a reason, 00:00:14.702 --> 00:00:16.764 because that is the number you might typically find 00:00:16.764 --> 00:00:19.595 in the belly of a single infected child. NOTE Paragraph 00:00:19.595 --> 00:00:22.079 Worm infections have been around for thousands of years. 00:00:22.079 --> 00:00:23.817 They have influenced the outcomes of wars, 00:00:23.817 --> 00:00:25.954 and they have long stymied human health. 00:00:25.954 --> 00:00:27.536 Roundworm, hookworm, 00:00:27.536 --> 00:00:29.898 whipworm, schistosomiasis: 00:00:29.898 --> 00:00:33.111 infections from these species cause pain and discomfort. 00:00:33.111 --> 00:00:35.151 They steal nutrients and zap energy. 00:00:35.151 --> 00:00:37.649 They both physical and cognitive growth. NOTE Paragraph 00:00:37.649 --> 00:00:40.395 In most cases, these worms may not be fatal, 00:00:40.395 --> 00:00:42.630 but paradoxically, that's part of the problem. 00:00:42.630 --> 00:00:45.177 It means that many countries simply have not been able 00:00:45.177 --> 00:00:46.918 to prioritize their treatment. 00:00:46.918 --> 00:00:48.676 There's a social cost to that: 00:00:48.676 --> 00:00:50.781 children without access to deworming treatments 00:00:50.781 --> 00:00:52.842 have lower rates of school attendants. 00:00:52.842 --> 00:00:55.040 Adults who grow up without deworming medicine 00:00:55.040 --> 00:00:57.494 are less productive and have lower lifelong earnings. 00:00:57.494 --> 00:01:00.856 What intestinal worms do, really, 00:01:00.856 --> 00:01:01.961 is limit potential. NOTE Paragraph 00:01:01.961 --> 00:01:05.599 Currently, there are 1.7 billion people in the world still at risk for worms. 00:01:05.664 --> 00:01:08.150 Six hundred million of them are in Africa. 00:01:08.150 --> 00:01:10.936 For every dollar invested in worm control and prevention, 00:01:10.936 --> 00:01:14.960 African countries see up to 42 dollars return in economic benefits. NOTE Paragraph 00:01:15.229 --> 00:01:18.495 The good news is that deworming treatment is extremely easy. 00:01:18.495 --> 00:01:20.668 One to three pills given once or twice a year 00:01:20.668 --> 00:01:23.730 is enough to take a child from 200 worms to zero 00:01:23.730 --> 00:01:26.275 and to protect them from infection going forward. 00:01:26.275 --> 00:01:28.742 In communities where there's a high prevalence of worms, 00:01:28.742 --> 00:01:30.766 treatment can be done right at school. 00:01:30.766 --> 00:01:33.328 This process is extremely simple and fast. 00:01:33.328 --> 00:01:36.389 In Ethiopia, for example, this is done for 20 million children 00:01:36.389 --> 00:01:37.859 in a matter of weeks. NOTE Paragraph 00:01:37.859 --> 00:01:41.553 The world has come a long way on getting deworming medicines 00:01:41.553 --> 00:01:43.192 to the people who need them, 00:01:43.192 --> 00:01:45.569 and African governments want to gain more traction. 00:01:45.569 --> 00:01:47.730 It's now time to match their ambition. NOTE Paragraph 00:01:47.730 --> 00:01:50.750 The END Fund will work with governments 00:01:50.750 --> 00:01:54.641 to create a plan that drastically reduces the burden of disease caused by worms. 00:01:54.641 --> 00:01:57.867 They will work together to ensure prevention and treatment programs 00:01:57.867 --> 00:01:59.121 can serve everyone. 00:01:59.121 --> 00:02:01.383 The END Fund has an audacious idea: 00:02:01.383 --> 00:02:05.728 they believe we are the generation to end sickness from worm infections forever. 00:02:05.728 --> 00:02:08.899 The key is not simply to build new programs from scratch, 00:02:08.899 --> 00:02:12.272 but to amplify the efforts of the programs that are already taking shape. 00:02:12.272 --> 00:02:15.961 By examining the problem of how worms transmit disease, 00:02:15.961 --> 00:02:19.652 the END Fund has identified five key areas where they can drive improvement. NOTE Paragraph 00:02:20.035 --> 00:02:22.732 Number one: lower the cost of treatment. 00:02:22.732 --> 00:02:25.750 Many pharmaceutical companies offer deworming medicines for free, 00:02:25.750 --> 00:02:27.602 so the END Fund works with the right partners 00:02:27.602 --> 00:02:29.463 to coordinate their delivery. 00:02:29.463 --> 00:02:31.869 They will continue to secure drug donations 00:02:31.869 --> 00:02:34.620 for additional at risk populations. 00:02:34.620 --> 00:02:38.804 They can now do it for less than 25 cents per child per year. 00:02:39.320 --> 00:02:41.774 Number two: focus on prevention. 00:02:41.774 --> 00:02:44.999 The END Fund calls in the right partners to educate communities 00:02:44.999 --> 00:02:46.489 on sanitation and hygiene 00:02:46.489 --> 00:02:49.288 in order to change behaviors around things like hand-washing 00:02:49.288 --> 00:02:50.181 and latrine use, 00:02:50.181 --> 00:02:52.725 ensuring people are not continually reinfected. NOTE Paragraph 00:02:53.207 --> 00:02:55.939 Number three: invest in innovation. 00:02:55.939 --> 00:02:58.193 The END Fund has contributed to deworming 00:02:58.193 --> 00:03:02.287 by introducing innovative techniques that effectively target and treat people. 00:03:02.287 --> 00:03:04.243 They will test new delivery methods, 00:03:04.243 --> 00:03:06.266 target the environments where parasites thrive, 00:03:06.266 --> 00:03:07.990 and influence behavior change. NOTE Paragraph 00:03:07.990 --> 00:03:10.567 Number four: monitor and evaluate. 00:03:10.567 --> 00:03:14.546 The END Fund collects detailed data on all programs on a regular basis 00:03:14.546 --> 00:03:17.104 to help them get better and better over time. NOTE Paragraph 00:03:17.104 --> 00:03:19.951 Number five: increase local ownership. 00:03:20.219 --> 00:03:21.955 At all stages of the process, 00:03:21.955 --> 00:03:24.982 the END Fund works with government and local stakeholders 00:03:24.982 --> 00:03:28.784 to encourage co-financing commitments that supports deworming efforts. 00:03:28.784 --> 00:03:31.080 They also worked with African philanthropists 00:03:31.080 --> 00:03:33.705 and corporate leaders to partner on these efforts. NOTE Paragraph 00:03:33.705 --> 00:03:37.472 There's an incredible opportunity to work together to create a new system 00:03:37.472 --> 00:03:40.776 for disease elimination for the next decade and beyond. 00:03:40.776 --> 00:03:42.688 Part of the money the END Fund needs 00:03:42.688 --> 00:03:45.193 will go directly toward delivering deworming treatments 00:03:45.193 --> 00:03:46.705 to communities that need it, 00:03:46.705 --> 00:03:50.027 and part will go towards facilitating the handover of programs 00:03:50.027 --> 00:03:51.370 to local ownership. 00:03:51.370 --> 00:03:54.928 Together, these efforts will create prevention and treatment programs 00:03:54.928 --> 00:03:57.298 that are sustainable far into the future. 00:03:57.298 --> 00:04:00.791 If this plan gets fully funded for the next six years, 00:04:00.791 --> 00:04:04.735 tens of millions of people will receive deworming treatment. 00:04:04.735 --> 00:04:08.730 With that, countries will be interrupting the cycle of disease transmission 00:04:08.730 --> 00:04:10.024 at all levels, 00:04:10.024 --> 00:04:14.349 and, most importantly, people will experience significant improvements 00:04:14.349 --> 00:04:16.876 in their mental, physical, and social health. NOTE Paragraph 00:04:16.876 --> 00:04:19.450 Just imagine the potential that will be gained 00:04:19.665 --> 00:04:21.997 when people can stop worrying about these 00:04:21.997 --> 00:04:25.690 and can put their energy to things like these.