[Script Info] Title: [Events] Format: Layer, Start, End, Style, Name, MarginL, MarginR, MarginV, Effect, Text Dialogue: 0,0:04:25.33,0:04:27.05,Default,,0000,0000,0000,,(Students' overlapping voices) Dialogue: 0,0:04:27.07,0:04:30.26,Default,,0000,0000,0000,,(Clapping and singing) Dialogue: 0,0:04:30.28,0:04:33.12,Default,,0000,0000,0000,,(Cheering) Dialogue: 0,0:04:33.42,0:04:35.21,Default,,0000,0000,0000,,[The Audacious Project] Dialogue: 0,0:00:00.48,0:00:02.06,Default,,0000,0000,0000,,These are worms. Dialogue: 0,0:00:02.09,0:00:04.68,Default,,0000,0000,0000,,Not the kind of worms\Nyou find crawling in the dirt. Dialogue: 0,0:00:04.70,0:00:06.85,Default,,0000,0000,0000,,These are parasitic roundworms. Dialogue: 0,0:00:06.88,0:00:09.31,Default,,0000,0000,0000,,They live inside\Na human being's intestines. Dialogue: 0,0:00:09.34,0:00:12.09,Default,,0000,0000,0000,,Each of these worms\Ncan grow up to 12 inches long, Dialogue: 0,0:00:12.12,0:00:14.50,Default,,0000,0000,0000,,and there are 200 of them\Nin this jar for a reason, Dialogue: 0,0:00:14.52,0:00:16.90,Default,,0000,0000,0000,,because that is the number\Nyou might typically find Dialogue: 0,0:00:16.93,0:00:19.37,Default,,0000,0000,0000,,in the belly of a single infected child. Dialogue: 0,0:00:19.40,0:00:22.06,Default,,0000,0000,0000,,Worm infections have been around\Nfor thousands of years. Dialogue: 0,0:00:22.08,0:00:24.08,Default,,0000,0000,0000,,They have influenced the outcomes of wars, Dialogue: 0,0:00:24.10,0:00:26.02,Default,,0000,0000,0000,,and they have long stymied human health. Dialogue: 0,0:00:26.04,0:00:27.63,Default,,0000,0000,0000,,Roundworm, hookworm, Dialogue: 0,0:00:27.65,0:00:29.67,Default,,0000,0000,0000,,whipworm, schistosomiasis: Dialogue: 0,0:00:29.70,0:00:32.81,Default,,0000,0000,0000,,infections from these species\Ncause pain and discomfort. Dialogue: 0,0:00:32.83,0:00:34.93,Default,,0000,0000,0000,,They steal nutrients and zap energy. Dialogue: 0,0:00:34.95,0:00:37.42,Default,,0000,0000,0000,,They stunt both physical\Nand cognitive growth. Dialogue: 0,0:00:37.45,0:00:40.17,Default,,0000,0000,0000,,In most cases, these worms\Nmay not be fatal, Dialogue: 0,0:00:40.20,0:00:42.37,Default,,0000,0000,0000,,but paradoxically,\Nthat's part of the problem. Dialogue: 0,0:00:42.40,0:00:43.94,Default,,0000,0000,0000,,It means that many countries Dialogue: 0,0:00:43.96,0:00:46.69,Default,,0000,0000,0000,,simply have not been able\Nto prioritize their treatment. Dialogue: 0,0:00:46.72,0:00:48.34,Default,,0000,0000,0000,,There's a social cost to that: Dialogue: 0,0:00:48.36,0:00:50.55,Default,,0000,0000,0000,,children without access\Nto deworming treatments Dialogue: 0,0:00:50.58,0:00:52.62,Default,,0000,0000,0000,,have lower rates of school attendance. Dialogue: 0,0:00:52.64,0:00:54.75,Default,,0000,0000,0000,,Adults who grow up\Nwithout deworming medicine Dialogue: 0,0:00:54.78,0:00:57.58,Default,,0000,0000,0000,,are less productive\Nand have lower lifelong earnings. Dialogue: 0,0:00:57.60,0:00:59.71,Default,,0000,0000,0000,,What intestinal worms do, really, Dialogue: 0,0:00:59.74,0:01:01.16,Default,,0000,0000,0000,,is limit potential. Dialogue: 0,0:01:01.19,0:01:05.41,Default,,0000,0000,0000,,Currently, there are 1.7 billion people\Nin the world still at risk for worms. Dialogue: 0,0:01:05.43,0:01:07.88,Default,,0000,0000,0000,,Six hundred million of them are in Africa. Dialogue: 0,0:01:07.90,0:01:11.03,Default,,0000,0000,0000,,For every dollar invested\Nin worm control and prevention, Dialogue: 0,0:01:11.05,0:01:15.20,Default,,0000,0000,0000,,African countries see up to 42 dollars'\Nreturn in economic benefits. Dialogue: 0,0:01:15.23,0:01:18.27,Default,,0000,0000,0000,,The good news is that deworming\Ntreatment is extremely easy. Dialogue: 0,0:01:18.30,0:01:20.54,Default,,0000,0000,0000,,One to three pills\Ngiven once or twice a year Dialogue: 0,0:01:20.56,0:01:23.60,Default,,0000,0000,0000,,is enough to take a child\Nfrom 200 worms to zero Dialogue: 0,0:01:23.63,0:01:26.05,Default,,0000,0000,0000,,and to protect them\Nfrom infection going forward. Dialogue: 0,0:01:26.08,0:01:28.70,Default,,0000,0000,0000,,In communities where\Nthere's a high prevalence of worms, Dialogue: 0,0:01:28.72,0:01:30.54,Default,,0000,0000,0000,,treatment can be done right at school. Dialogue: 0,0:01:30.86,0:01:33.19,Default,,0000,0000,0000,,This process is extremely simple and fast. Dialogue: 0,0:01:33.21,0:01:36.34,Default,,0000,0000,0000,,In Ethiopia, for example,\Nthis is done for 20 million children Dialogue: 0,0:01:36.36,0:01:38.15,Default,,0000,0000,0000,,in a matter of weeks. Dialogue: 0,0:01:38.17,0:01:39.80,Default,,0000,0000,0000,,The world has come a long way Dialogue: 0,0:01:39.82,0:01:42.65,Default,,0000,0000,0000,,on getting deworming medicines\Nto the people who need them, Dialogue: 0,0:01:42.67,0:01:45.21,Default,,0000,0000,0000,,and African governments\Nwant to gain more traction. Dialogue: 0,0:01:45.24,0:01:47.35,Default,,0000,0000,0000,,It's now time to match their ambition. Dialogue: 0,0:01:47.73,0:01:49.67,Default,,0000,0000,0000,,The END Fund will work with governments Dialogue: 0,0:01:49.70,0:01:54.42,Default,,0000,0000,0000,,to create a plan that drastically reduces\Nthe burden of disease caused by worms. Dialogue: 0,0:01:54.44,0:01:57.58,Default,,0000,0000,0000,,They’ll work together to ensure\Nprevention and treatment programs Dialogue: 0,0:01:57.60,0:01:58.90,Default,,0000,0000,0000,,can serve everyone. Dialogue: 0,0:01:58.92,0:02:01.10,Default,,0000,0000,0000,,The END Fund has an audacious idea: Dialogue: 0,0:02:01.12,0:02:05.50,Default,,0000,0000,0000,,they believe we are the generation to end\Nsickness from worm infections forever. Dialogue: 0,0:02:05.53,0:02:08.72,Default,,0000,0000,0000,,The key is not simply to build\Nnew programs from scratch, Dialogue: 0,0:02:08.75,0:02:12.39,Default,,0000,0000,0000,,but to amplify the efforts of the programs\Nthat are already taking shape. Dialogue: 0,0:02:12.41,0:02:15.52,Default,,0000,0000,0000,,By examining the problem\Nof how worms transmit disease, Dialogue: 0,0:02:15.55,0:02:19.47,Default,,0000,0000,0000,,the END Fund has identified five key areas\Nwhere they can drive improvement. Dialogue: 0,0:02:20.02,0:02:22.46,Default,,0000,0000,0000,,Number one: lower the cost of treatment. Dialogue: 0,0:02:22.48,0:02:25.53,Default,,0000,0000,0000,,Many pharmaceutical companies\Noffer deworming medicines for free, Dialogue: 0,0:02:25.56,0:02:27.70,Default,,0000,0000,0000,,so the END Fund\Nworks with the right partners Dialogue: 0,0:02:27.72,0:02:29.29,Default,,0000,0000,0000,,to coordinate their delivery. Dialogue: 0,0:02:29.32,0:02:31.74,Default,,0000,0000,0000,,They will continue\Nto secure drug donations Dialogue: 0,0:02:31.76,0:02:34.40,Default,,0000,0000,0000,,for additional at-risk populations. Dialogue: 0,0:02:34.98,0:02:38.76,Default,,0000,0000,0000,,They can now do it for less\Nthan 25 cents per child per year. Dialogue: 0,0:02:39.12,0:02:41.55,Default,,0000,0000,0000,,Number two: focus on prevention. Dialogue: 0,0:02:41.57,0:02:44.58,Default,,0000,0000,0000,,The END Fund calls in the right partners\Nto educate communities Dialogue: 0,0:02:44.60,0:02:46.17,Default,,0000,0000,0000,,on sanitation and hygiene Dialogue: 0,0:02:46.19,0:02:49.04,Default,,0000,0000,0000,,in order to change behaviors\Naround things like hand-washing Dialogue: 0,0:02:49.06,0:02:50.21,Default,,0000,0000,0000,,and latrine use, Dialogue: 0,0:02:50.23,0:02:52.93,Default,,0000,0000,0000,,ensuring people\Nare not continually reinfected. Dialogue: 0,0:02:52.95,0:02:55.66,Default,,0000,0000,0000,,Number three: invest in innovation. Dialogue: 0,0:02:55.68,0:02:57.76,Default,,0000,0000,0000,,The END Fund has contributed to deworming Dialogue: 0,0:02:57.78,0:03:02.02,Default,,0000,0000,0000,,by introducing innovative techniques\Nthat effectively target and treat people. Dialogue: 0,0:03:02.05,0:03:03.82,Default,,0000,0000,0000,,They will test new delivery methods, Dialogue: 0,0:03:03.84,0:03:06.03,Default,,0000,0000,0000,,target the environments\Nwhere parasites thrive, Dialogue: 0,0:03:06.06,0:03:07.77,Default,,0000,0000,0000,,and influence behavior change. Dialogue: 0,0:03:07.79,0:03:10.50,Default,,0000,0000,0000,,Number four: monitor and evaluate. Dialogue: 0,0:03:10.53,0:03:14.32,Default,,0000,0000,0000,,The END Fund collects detailed data\Non all programs on a regular basis Dialogue: 0,0:03:14.35,0:03:17.06,Default,,0000,0000,0000,,to help them get better\Nand better over time. Dialogue: 0,0:03:17.08,0:03:19.92,Default,,0000,0000,0000,,Number five: increase local ownership. Dialogue: 0,0:03:19.95,0:03:21.57,Default,,0000,0000,0000,,At all stages of the process, Dialogue: 0,0:03:21.59,0:03:24.76,Default,,0000,0000,0000,,the END Fund works with government\Nand local stakeholders Dialogue: 0,0:03:24.78,0:03:28.56,Default,,0000,0000,0000,,to encourage cofinancing commitments\Nthat support deworming efforts. Dialogue: 0,0:03:28.58,0:03:30.76,Default,,0000,0000,0000,,They also worked\Nwith African philanthropists Dialogue: 0,0:03:30.78,0:03:33.63,Default,,0000,0000,0000,,and corporate leaders\Nto partner on these efforts. Dialogue: 0,0:03:33.66,0:03:37.38,Default,,0000,0000,0000,,There's an incredible opportunity\Nto work together to create a new system Dialogue: 0,0:03:37.40,0:03:40.62,Default,,0000,0000,0000,,for disease elimination\Nfor the next decade and beyond. Dialogue: 0,0:03:40.65,0:03:42.40,Default,,0000,0000,0000,,Part of the money the END Fund needs Dialogue: 0,0:03:42.43,0:03:45.03,Default,,0000,0000,0000,,will go directly toward delivering\Ndeworming treatments Dialogue: 0,0:03:45.05,0:03:46.45,Default,,0000,0000,0000,,to communities that need it, Dialogue: 0,0:03:46.47,0:03:49.89,Default,,0000,0000,0000,,and part will go towards facilitating\Nthe handover of programs Dialogue: 0,0:03:49.92,0:03:51.22,Default,,0000,0000,0000,,to local ownership. Dialogue: 0,0:03:51.24,0:03:54.70,Default,,0000,0000,0000,,Together, these efforts will create\Nprevention and treatment programs Dialogue: 0,0:03:54.73,0:03:57.31,Default,,0000,0000,0000,,that are sustainable far into the future. Dialogue: 0,0:03:57.34,0:04:00.83,Default,,0000,0000,0000,,If this plan gets fully funded\Nfor the next six years, Dialogue: 0,0:04:00.85,0:04:04.51,Default,,0000,0000,0000,,tens of millions of people\Nwill receive deworming treatment. Dialogue: 0,0:04:04.88,0:04:08.60,Default,,0000,0000,0000,,With that, countries will be interrupting\Nthe cycle of disease transmission Dialogue: 0,0:04:08.63,0:04:09.80,Default,,0000,0000,0000,,at all levels, Dialogue: 0,0:04:09.82,0:04:13.68,Default,,0000,0000,0000,,and, most importantly, people\Nwill experience significant improvements Dialogue: 0,0:04:13.70,0:04:16.65,Default,,0000,0000,0000,,in their mental, physical,\Nand social health. Dialogue: 0,0:04:16.68,0:04:19.19,Default,,0000,0000,0000,,Just imagine the potential\Nthat will be gained Dialogue: 0,0:04:19.22,0:04:21.64,Default,,0000,0000,0000,,when people can stop worrying about these Dialogue: 0,0:04:21.66,0:04:24.51,Default,,0000,0000,0000,,and can put their energy\Ninto things like these.