1 00:04:25,331 --> 00:04:27,050 (Students' overlapping voices) 2 00:04:27,074 --> 00:04:30,257 (Clapping and singing) 3 00:04:30,281 --> 00:04:33,121 (Cheering) 4 00:00:00,482 --> 00:00:02,065 These are worms. 5 00:00:02,089 --> 00:00:04,675 Not the kind of worms you find crawling in the dirt. 6 00:00:04,699 --> 00:00:06,853 These are parasitic roundworms. 7 00:00:06,877 --> 00:00:09,312 They live inside a human being's intestines. 8 00:00:09,336 --> 00:00:12,092 Each of these worms can grow up to 12 inches long, 9 00:00:12,116 --> 00:00:14,497 and there are 200 of them in this jar for a reason, 10 00:00:14,521 --> 00:00:16,903 because that is the number you might typically find 11 00:00:16,927 --> 00:00:19,371 in the belly of a single infected child. 12 00:00:19,395 --> 00:00:22,055 Worm infections have been around for thousands of years. 13 00:00:22,079 --> 00:00:24,079 They have influenced the outcomes of wars, 14 00:00:24,103 --> 00:00:26,016 and they have long stymied human health. 15 00:00:26,040 --> 00:00:27,627 Roundworm, hookworm, 16 00:00:27,651 --> 00:00:29,674 whipworm, schistosomiasis: 17 00:00:29,698 --> 00:00:32,810 infections from these species cause pain and discomfort. 18 00:00:32,834 --> 00:00:34,927 They steal nutrients and zap energy. 19 00:00:34,951 --> 00:00:37,425 They stunt both physical and cognitive growth. 20 00:00:37,449 --> 00:00:40,171 In most cases, these worms may not be fatal, 21 00:00:40,195 --> 00:00:42,374 but paradoxically, that's part of the problem. 22 00:00:42,398 --> 00:00:43,938 It means that many countries 23 00:00:43,962 --> 00:00:46,694 simply have not been able to prioritize their treatment. 24 00:00:46,718 --> 00:00:48,335 There's a social cost to that: 25 00:00:48,359 --> 00:00:50,551 children without access to deworming treatments 26 00:00:50,575 --> 00:00:52,618 have lower rates of school attendance. 27 00:00:52,642 --> 00:00:54,754 Adults who grow up without deworming medicine 28 00:00:54,778 --> 00:00:57,578 are less productive and have lower lifelong earnings. 29 00:00:57,602 --> 00:00:59,714 What intestinal worms do, really, 30 00:00:59,738 --> 00:01:01,165 is limit potential. 31 00:01:01,189 --> 00:01:05,408 Currently, there are 1.7 billion people in the world still at risk for worms. 32 00:01:05,432 --> 00:01:07,878 Six hundred million of them are in Africa. 33 00:01:07,902 --> 00:01:11,028 For every dollar invested in worm control and prevention, 34 00:01:11,052 --> 00:01:15,203 African countries see up to 42 dollars return in economic benefits. 35 00:01:15,227 --> 00:01:18,271 The good news is that deworming treatment is extremely easy. 36 00:01:18,295 --> 00:01:20,540 One to three pills given once or twice a year 37 00:01:20,564 --> 00:01:23,604 is enough to take a child from 200 worms to zero 38 00:01:23,628 --> 00:01:26,051 and to protect them from infection going forward. 39 00:01:26,075 --> 00:01:28,695 In communities where there's a high prevalence of worms, 40 00:01:28,719 --> 00:01:30,542 treatment can be done right at school. 41 00:01:30,855 --> 00:01:33,188 This process is extremely simple and fast. 42 00:01:33,212 --> 00:01:36,338 In Ethiopia, for example, this is done for 20 million children 43 00:01:36,362 --> 00:01:38,148 in a matter of weeks. 44 00:01:38,172 --> 00:01:39,800 The world has come a long way 45 00:01:39,824 --> 00:01:42,649 on getting deworming medicines to the people who need them, 46 00:01:42,673 --> 00:01:45,213 and African governments want to gain more traction. 47 00:01:45,237 --> 00:01:47,346 It's now time to match their ambition. 48 00:01:47,729 --> 00:01:49,674 The END Fund will work with governments 49 00:01:49,698 --> 00:01:54,417 to create a plan that drastically reduces the burden of disease caused by worms. 50 00:01:54,441 --> 00:01:57,579 They’ll work together to ensure prevention and treatment programs 51 00:01:57,603 --> 00:01:58,897 can serve everyone. 52 00:01:58,921 --> 00:02:01,100 The END Fund has an audacious idea: 53 00:02:01,124 --> 00:02:05,504 they believe we are the generation to end sickness from worm infections forever. 54 00:02:05,528 --> 00:02:08,723 The key is not simply to build new programs from scratch, 55 00:02:08,747 --> 00:02:12,389 but to amplify the efforts of the programs that are already taking shape. 56 00:02:12,413 --> 00:02:15,525 By examining the problem of how worms transmit disease, 57 00:02:15,549 --> 00:02:19,469 the END Fund has identified five key areas where they can drive improvement. 58 00:02:20,017 --> 00:02:22,460 Number one: lower the cost of treatment. 59 00:02:22,484 --> 00:02:25,533 Many pharmaceutical companies offer deworming medicines for free, 60 00:02:25,557 --> 00:02:27,700 so the END Fund works with the right partners 61 00:02:27,724 --> 00:02:29,291 to coordinate their delivery. 62 00:02:29,315 --> 00:02:31,735 They will continue to secure drug donations 63 00:02:31,759 --> 00:02:34,396 for additional at-risk populations. 64 00:02:34,982 --> 00:02:38,760 They can now do it for less than 25 cents per child per year. 65 00:02:39,120 --> 00:02:41,550 Number two: focus on prevention. 66 00:02:41,574 --> 00:02:44,576 The END Fund calls in the right partners to educate communities 67 00:02:44,600 --> 00:02:46,169 on sanitation and hygiene 68 00:02:46,193 --> 00:02:49,035 in order to change behaviors around things like hand-washing 69 00:02:49,059 --> 00:02:50,210 and latrine use, 70 00:02:50,234 --> 00:02:52,927 ensuring people are not continually reinfected. 71 00:02:52,951 --> 00:02:55,660 Number three: invest in innovation. 72 00:02:55,684 --> 00:02:57,759 The END Fund has contributed to deworming 73 00:02:57,783 --> 00:03:02,023 by introducing innovative techniques that effectively target and treat people. 74 00:03:02,047 --> 00:03:03,815 They will test new delivery methods, 75 00:03:03,839 --> 00:03:06,031 target the environments where parasites thrive 76 00:03:06,055 --> 00:03:07,766 and influence behavior change. 77 00:03:07,790 --> 00:03:10,503 Number four: monitor and evaluate. 78 00:03:10,527 --> 00:03:14,322 The END Fund collects detailed data on all programs on a regular basis 79 00:03:14,346 --> 00:03:17,058 to help them get better and better over time. 80 00:03:17,082 --> 00:03:19,924 Number five: increase local ownership. 81 00:03:19,948 --> 00:03:21,567 At all stages of the process, 82 00:03:21,591 --> 00:03:24,758 the END Fund works with government and local stakeholders 83 00:03:24,782 --> 00:03:28,560 to encourage cofinancing commitments that support deworming efforts. 84 00:03:28,584 --> 00:03:30,760 They also worked with African philanthropists 85 00:03:30,784 --> 00:03:33,631 and corporate leaders to partner on these efforts. 86 00:03:33,655 --> 00:03:37,377 There's an incredible opportunity to work together to create a new system 87 00:03:37,401 --> 00:03:40,623 for disease elimination for the next decade and beyond. 88 00:03:40,647 --> 00:03:42,402 Part of the money the END Fund needs 89 00:03:42,426 --> 00:03:45,027 will go directly toward delivering deworming treatments 90 00:03:45,051 --> 00:03:46,449 to communities that need it 91 00:03:46,473 --> 00:03:49,894 and part will go towards facilitating the handover of programs 92 00:03:49,918 --> 00:03:51,219 to local ownership. 93 00:03:51,243 --> 00:03:54,704 Together, these efforts will create prevention and treatment programs 94 00:03:54,728 --> 00:03:57,314 that are sustainable far into the future. 95 00:03:57,338 --> 00:04:00,830 If this plan gets fully funded for the next six years, 96 00:04:00,854 --> 00:04:04,511 tens of millions of people will receive deworming treatment. 97 00:04:04,883 --> 00:04:08,605 With that, countries will be interrupting the cycle of disease transmission 98 00:04:08,629 --> 00:04:09,800 at all levels, 99 00:04:09,824 --> 00:04:13,677 and most importantly, people will experience significant improvements 100 00:04:13,701 --> 00:04:16,652 in their mental, physical and social health. 101 00:04:16,676 --> 00:04:19,194 Just imagine the potential that will be gained 102 00:04:19,218 --> 00:04:21,637 when people can stop worrying about these 103 00:04:21,661 --> 00:04:24,510 and can put their energy into things like these.