WEBVTT 99:59:59.999 --> 99:59:59.999 Every single one of us will lose, 99:59:59.999 --> 99:59:59.999 or has already lost something we rely on every single day. 99:59:59.999 --> 99:59:59.999 I am of course talking about our keys. 99:59:59.999 --> 99:59:59.999 (Laughter) 99:59:59.999 --> 99:59:59.999 Just kidding. 99:59:59.999 --> 99:59:59.999 What I actually want to talk about is one of our most important senses: 99:59:59.999 --> 99:59:59.999 vision. 99:59:59.999 --> 99:59:59.999 Every single day we each lose a little bit of our ability 99:59:59.999 --> 99:59:59.999 to refocus our eyes 99:59:59.999 --> 99:59:59.999 until we can't refocus at all. 99:59:59.999 --> 99:59:59.999 We call this condition presbyopia, 99:59:59.999 --> 99:59:59.999 and it affects two billion people worldwide. 99:59:59.999 --> 99:59:59.999 That's right, I said billion. 99:59:59.999 --> 99:59:59.999 If you haven't heard of presbyopia, 99:59:59.999 --> 99:59:59.999 and you're wondering, "Where are these two billon people?" 99:59:59.999 --> 99:59:59.999 here's a hint before I get into the details. 99:59:59.999 --> 99:59:59.999 It's the reason why people wear reading glasses 99:59:59.999 --> 99:59:59.999 or bifocal lenses. 99:59:59.999 --> 99:59:59.999 I'll get started by describing the loss of refocusing ability 99:59:59.999 --> 99:59:59.999 leading up to presbyopia. 99:59:59.999 --> 99:59:59.999 As a newborn, 99:59:59.999 --> 99:59:59.999 you would have been able to focus as lose as six-and-a-half centimenters 99:59:59.999 --> 99:59:59.999 if you wish to. 99:59:59.999 --> 99:59:59.999 By your mid-20s, you have about half of that focusing power left. 99:59:59.999 --> 99:59:59.999 10 centimeters or so, 99:59:59.999 --> 99:59:59.999 but close enough that you never notice the difference. 99:59:59.999 --> 99:59:59.999 By your late-40s though, 99:59:59.999 --> 99:59:59.999 the closest you can focus is about 25 centimeters, 99:59:59.999 --> 99:59:59.999 maybe even farther. 99:59:59.999 --> 99:59:59.999 Losses in focusing ability beyond this point 99:59:59.999 --> 99:59:59.999 start effecting near-vision tasks like reading, 99:59:59.999 --> 99:59:59.999 and by the time you reach age 60, 99:59:59.999 --> 99:59:59.999 nothing within a meter radius of you is clear. 99:59:59.999 --> 99:59:59.999 Right now some of you are probably thinking, 99:59:59.999 --> 99:59:59.999 that sounds bad but he means you in a figurative sense, 99:59:59.999 --> 99:59:59.999 only for the people that actually end up with presbyopia. 99:59:59.999 --> 99:59:59.999 But no, when I say you, I literally mean that every single one of you 99:59:59.999 --> 99:59:59.999 will someday be presbyopic if you aren't already. 99:59:59.999 --> 99:59:59.999 That sounds a bit troubling. 99:59:59.999 --> 99:59:59.999 I want to remind you that presbyopia has been with us for all of human history 99:59:59.999 --> 99:59:59.999 and we've done a lot of different things to try and fix it. 99:59:59.999 --> 99:59:59.999 So to start, let's imagine that you're sitting at a desk reading. 99:59:59.999 --> 99:59:59.999 If you were presbyopic, 99:59:59.999 --> 99:59:59.999 it might look a little something like this. 99:59:59.999 --> 99:59:59.999 Anything close by, like the magazine, will be blurry. 99:59:59.999 --> 99:59:59.999 Moving on to solutions. 99:59:59.999 --> 99:59:59.999 First, reading glasses. 99:59:59.999 --> 99:59:59.999 These have lenses with a single focal power 99:59:59.999 --> 99:59:59.999 tuned so that near objects come into focus. 99:59:59.999 --> 99:59:59.999 But far objects necessary go out of focus, 99:59:59.999 --> 99:59:59.999 meaning you have to constantly switch back and forth 99:59:59.999 --> 99:59:59.999 between wearing and not wearing them. 99:59:59.999 --> 99:59:59.999 To solve this problem, 99:59:59.999 --> 99:59:59.999 Benjamin Franklin invented what he called "double spectacles." 99:59:59.999 --> 99:59:59.999 Today we call those bifocals, 99:59:59.999 --> 99:59:59.999 and what they let him do was see far when he looked up 99:59:59.999 --> 99:59:59.999 and see near when he looked down. 99:59:59.999 --> 99:59:59.999 Today we also have progressive lenses which get rid of the line 99:59:59.999 --> 99:59:59.999 by smoothly varying the focal power from top to bottom. 99:59:59.999 --> 99:59:59.999 The downside to both of these is that you lose field of vision 99:59:59.999 --> 99:59:59.999 at any given distance 99:59:59.999 --> 99:59:59.999 because it gets split up from top to bottom like this. 99:59:59.999 --> 99:59:59.999 To see why that's a problem, 99:59:59.999 --> 99:59:59.999 imagine that you're climbing down a ladder or stairs. 99:59:59.999 --> 99:59:59.999 You look down to get your footing but it's blurry. 99:59:59.999 --> 99:59:59.999 Why would it be blurry? 99:59:59.999 --> 99:59:59.999 Well, you look down, and that's the near part of the lens, 99:59:59.999 --> 99:59:59.999 but the next step was past arm's reach, 99:59:59.999 --> 99:59:59.999 which for your eyes, counts as far. 99:59:59.999 --> 99:59:59.999 The next solution I want to point out is a little less common 99:59:59.999 --> 99:59:59.999 but comes up a lot in contact lenses or Lasik surgeries, 99:59:59.999 --> 99:59:59.999 and it's called monovision. 99:59:59.999 --> 99:59:59.999 And it works but setting up the dominant eye to focus far 99:59:59.999 --> 99:59:59.999 and the other eye to focus near. 99:59:59.999 --> 99:59:59.999 Your brain does the work of intelligently putting together the sharpest parts 99:59:59.999 --> 99:59:59.999 from each eye's view, 99:59:59.999 --> 99:59:59.999 but the two eyes see slightly different things, 99:59:59.999 --> 99:59:59.999 and that makes it harder to judge distances binocularly. 99:59:59.999 --> 99:59:59.999 So where does that all leave us? 99:59:59.999 --> 99:59:59.999 It seems like we've come up with a lot of different solutions 99:59:59.999 --> 99:59:59.999 but none of them quite restore natural refocusing. 99:59:59.999 --> 99:59:59.999 None of them let you just look at something 99:59:59.999 --> 99:59:59.999 and expect it to be in focus. 99:59:59.999 --> 99:59:59.999 But why? 99:59:59.999 --> 99:59:59.999 Well, to explain that, we'll want to take a look at the anatomy 99:59:59.999 --> 99:59:59.999 of the human eye. 99:59:59.999 --> 99:59:59.999 The part of the eye that allows us to refocus to different distances 99:59:59.999 --> 99:59:59.999 is called the crystalline lens. 99:59:59.999 --> 99:59:59.999 There are muscles surrounding the lens that can deform it into different shapes, 99:59:59.999 --> 99:59:59.999 which in turn changes its focusing power. 99:59:59.999 --> 99:59:59.999 What happens when someone becomes presbyopic? 99:59:59.999 --> 99:59:59.999 It turns out that the crystalline lens stiffens to the point 99:59:59.999 --> 99:59:59.999 that it doesn't really change shape anymore. 99:59:59.999 --> 99:59:59.999 Now, thinking back on all the solutions I listed earlier, 99:59:59.999 --> 99:59:59.999 we can see that they all have something in common with the others 99:59:59.999 --> 99:59:59.999 but not with our eyes, 99:59:59.999 --> 99:59:59.999 and that is that they're all static. 99:59:59.999 --> 99:59:59.999 It's like the optical equivalent of a pirate with a peg leg. 99:59:59.999 --> 99:59:59.999 What is the optical equivalent of a modern prosthetic leg? 99:59:59.999 --> 99:59:59.999 The last several decades have seen the creation and rapid development 99:59:59.999 --> 99:59:59.999 of what are called "focus-tunable lenses." 99:59:59.999 --> 99:59:59.999 There are several different types. 99:59:59.999 --> 99:59:59.999 Mechanically-shifting Alvarez lenses, 99:59:59.999 --> 99:59:59.999 deformable liquid lenses 99:59:59.999 --> 99:59:59.999 and electronically-switched, liquid-crystal lenses. 99:59:59.999 --> 99:59:59.999 Now these have their own tradeoffs, 99:59:59.999 --> 99:59:59.999 but what they don't skimp on is the visual experience. 99:59:59.999 --> 99:59:59.999 Full field-of-view vision that can be sharp at any desirable distance. 99:59:59.999 --> 99:59:59.999 OK, great. 99:59:59.999 --> 99:59:59.999 The lenses we need already exist; 99:59:59.999 --> 99:59:59.999 problem solved, right? 99:59:59.999 --> 99:59:59.999 Not so fast. 99:59:59.999 --> 99:59:59.999 Focus-tunable lenses add a bit of complexity to the equation. 99:59:59.999 --> 99:59:59.999 The lenses don't have any way of knowing what distance 99:59:59.999 --> 99:59:59.999 they should be focused to. 99:59:59.999 --> 99:59:59.999 What we really need are glasses that, when you're looking far, 99:59:59.999 --> 99:59:59.999 far objects are sharp, 99:59:59.999 --> 99:59:59.999 and when you're looking near, 99:59:59.999 --> 99:59:59.999 near objects come into focus 99:59:59.999 --> 99:59:59.999 anywhere in your field of view and without you having to think about it. 99:59:59.999 --> 99:59:59.999 What I've worked on these last few years at Stamford 99:59:59.999 --> 99:59:59.999 is building that exact intelligence around the lenses. 99:59:59.999 --> 99:59:59.999 Our prototype borrows technology from virtual and augmented reality systems 99:59:59.999 --> 99:59:59.999 to estimate focusing distance. 99:59:59.999 --> 99:59:59.999 We have an eye tracker that can help tell what direction our eyes are focused in. 99:59:59.999 --> 99:59:59.999 Using two of these, 99:59:59.999 --> 99:59:59.999 we can directly triangulate your gaze direction 99:59:59.999 --> 99:59:59.999 to get a focus estimate. 99:59:59.999 --> 99:59:59.999 Just in case though, 99:59:59.999 --> 99:59:59.999 to increase reliability we also added a distance censor. 99:59:59.999 --> 99:59:59.999 The censor is a camera that looks out at the world 99:59:59.999 --> 99:59:59.999 and reports distances to objects. 99:59:59.999 --> 99:59:59.999 We can again use your gaze direction to get a distance estimate 99:59:59.999 --> 99:59:59.999 for a second time. 99:59:59.999 --> 99:59:59.999 We then fuse those two distance estimates 99:59:59.999 --> 99:59:59.999 and update the focus-tunable lens power accordingly. 99:59:59.999 --> 99:59:59.999 The next step for us was of course to test our device on actual people. 99:59:59.999 --> 99:59:59.999 So we recruited about 100 presbyopes and had them test our device 99:59:59.999 --> 99:59:59.999 while we measured their performance. 99:59:59.999 --> 99:59:59.999 What we saw convinced us right then that autofocals were the future. 99:59:59.999 --> 99:59:59.999 Our participants could see more clearly, 99:59:59.999 --> 99:59:59.999 they could focus more quickly 99:59:59.999 --> 99:59:59.999 and they thought it was an easier and better focusing experience 99:59:59.999 --> 99:59:59.999 than their current correction. 99:59:59.999 --> 99:59:59.999 Put it simply: 99:59:59.999 --> 99:59:59.999 when it comes to vision, 99:59:59.999 --> 99:59:59.999 autofocals don't compromise like static corrections in use today do. 99:59:59.999 --> 99:59:59.999 But I don't want to get ahead of myself. 99:59:59.999 --> 99:59:59.999 There's a lot of work for my colleagues and me left to do. 99:59:59.999 --> 99:59:59.999 For example, our glasses are a bit -- 99:59:59.999 --> 99:59:59.999 (Laughter) 99:59:59.999 --> 99:59:59.999 bulky, maybe? 99:59:59.999 --> 99:59:59.999 And one reason for this is that we used bulkier components 99:59:59.999 --> 99:59:59.999 that are often intended for research use or industrial use. 99:59:59.999 --> 99:59:59.999 Another is that we need to strap everything down 99:59:59.999 --> 99:59:59.999 because current eye-tracking algorithms don't have the robustness that we need. 99:59:59.999 --> 99:59:59.999 So moving forward, 99:59:59.999 --> 99:59:59.999 as we move from a research setting to a start-up, 99:59:59.999 --> 99:59:59.999 we plan to make future autofocals 99:59:59.999 --> 99:59:59.999 eventually look a little bit more like normal glasses. 99:59:59.999 --> 99:59:59.999 For this to happen, 99:59:59.999 --> 99:59:59.999 we'll need to significantly improve 99:59:59.999 --> 99:59:59.999 the robustness of our eye-tracking solution. 99:59:59.999 --> 99:59:59.999 We'll also need to incorporate smaller and more efficient electronics and lenses. 99:59:59.999 --> 99:59:59.999 That said, even with our current prototype, 99:59:59.999 --> 99:59:59.999 we've shown that today's focus-tunable lens technology 99:59:59.999 --> 99:59:59.999 is capable of out-performing traditional forms of static correction. 99:59:59.999 --> 99:59:59.999 So it's only a matter of time. 99:59:59.999 --> 99:59:59.999 It's clear that in the near future, 99:59:59.999 --> 99:59:59.999 instead of worrying about which pair of glasses to use and when, 99:59:59.999 --> 99:59:59.999 we'll be able to just focus on the important things. 99:59:59.999 --> 99:59:59.999 (Applause) 99:59:59.999 --> 99:59:59.999 Thank you. 99:59:59.999 --> 99:59:59.999 (Applause)