WEBVTT 00:00:00.891 --> 00:00:02.854 Every single one of us will lose 00:00:02.854 --> 00:00:06.011 or has already lost something we rely on every single day. 00:00:06.721 --> 00:00:09.222 I am of course talking about our keys. 00:00:09.530 --> 00:00:10.931 (Laughter) 00:00:11.194 --> 00:00:12.210 Just kidding. 00:00:12.210 --> 00:00:15.542 What I actually want to talk about is one of our most important senses: 00:00:15.542 --> 00:00:16.536 vision. 00:00:16.536 --> 00:00:19.260 Every single day we each lose a little bit of our ability 00:00:19.260 --> 00:00:20.594 to refocus our eyes 00:00:20.594 --> 00:00:22.328 until we can't refocus at all. 00:00:22.837 --> 00:00:24.960 We call this condition presbyopia, 00:00:24.960 --> 00:00:27.324 and it affects two billion people worldwide. 00:00:27.554 --> 00:00:29.324 That's right, I said billion. 00:00:29.524 --> 00:00:31.204 If you haven't heard of presbyopia, 00:00:31.204 --> 00:00:34.010 and you're wondering, "Where are these two billion people?" 00:00:34.010 --> 00:00:36.074 here's a hint before I get into the details. 00:00:36.074 --> 00:00:39.217 It's the reason why people wear reading glasses or bifocal lenses. 00:00:39.537 --> 00:00:42.435 I'll get started by describing the loss in refocusing ability 00:00:42.435 --> 00:00:43.774 leading up to presbyopia. 00:00:43.952 --> 00:00:44.968 As a newborn, 00:00:44.968 --> 00:00:48.415 you would have been able to focus as lose as six-and-a-half centimenters 00:00:48.415 --> 00:00:49.636 if you wish to. 00:00:49.636 --> 00:00:52.698 By your mid-20s, you have about half of that focusing power left. 00:00:52.734 --> 00:00:53.950 10 centimeters or so, 00:00:53.950 --> 00:00:56.485 but close enough that you never notice the difference. 00:00:56.485 --> 00:00:57.640 By your late-40s though, 00:00:57.640 --> 00:01:00.008 the closest you can focus is about 25 centimeters, 00:01:00.008 --> 00:01:01.242 maybe even farther. 00:01:01.242 --> 00:01:03.316 Losses in focusing ability beyond this point 00:01:03.316 --> 00:01:05.526 start effecting near-vision tasks like reading, 00:01:05.526 --> 00:01:07.489 and by the time you reach age 60, 00:01:07.489 --> 00:01:09.992 nothing within a meter radius of you is clear. 00:01:10.168 --> 00:01:12.335 Right now some of you are probably thinking, 00:01:12.335 --> 00:01:15.683 that sounds bad but he means you in a figurative sense, 00:01:15.683 --> 00:01:18.622 only for the people that actually end up with presbyopia. 00:01:19.128 --> 00:01:23.578 But no, when I say you, I literally mean that every single one of you 00:01:23.578 --> 00:01:26.429 will someday be presbyopic if you aren't already. 00:01:26.852 --> 00:01:28.237 That sounds a bit troubling. 00:01:28.237 --> 00:01:31.901 I want to remind you that presbyopia has been with us for all of human history 00:01:31.901 --> 00:01:34.724 and we've done a lot of different things to try and fix it. 00:01:34.730 --> 00:01:38.457 So to start, let's imagine that you're sitting at a desk, reading. 00:01:38.699 --> 00:01:40.091 If you were presbyopic, 00:01:40.091 --> 00:01:42.098 it might look a little something like this. 00:01:42.098 --> 00:01:44.840 Anything close by, like the magazine, will be blurry. 00:01:45.196 --> 00:01:46.454 Moving on to solutions. 00:01:46.454 --> 00:01:48.044 First, reading glasses. 00:01:48.285 --> 00:01:50.317 These have lenses with a single focal power 00:01:50.328 --> 00:01:52.408 tuned so that near objects come into focus. 00:01:52.609 --> 00:01:55.322 But far objects necessarily go out of focus, 00:01:55.322 --> 00:01:57.763 meaning you have to constantly switch back and forth 00:01:57.763 --> 00:01:59.535 between wearing and not wearing them. 00:01:59.535 --> 00:02:00.759 To solve this problem 00:02:00.759 --> 00:02:04.026 Benjamin Franklin invented what he called "double spectacles." 00:02:04.241 --> 00:02:06.249 Today we call those bifocals, 00:02:06.249 --> 00:02:09.837 and what they let him do was see far when he looked up 00:02:09.837 --> 00:02:11.459 and see near when he looked down. 00:02:11.459 --> 00:02:14.463 Today we also have progressive lenses which get rid of the line 00:02:14.463 --> 00:02:17.033 by smoothly varying the focal power from top to bottom. 00:02:17.033 --> 00:02:18.445 The downside to both of these 00:02:18.445 --> 00:02:21.244 is that you lose field of vision at any given distance 00:02:21.244 --> 00:02:23.811 because it gets split up from top to bottom like this. 00:02:23.811 --> 00:02:25.180 To see why that's a problem, 00:02:25.180 --> 00:02:27.975 imagine that you're climbing down a ladder or stairs. 00:02:28.166 --> 00:02:31.325 You look down to get your footing but it's blurry. 00:02:31.691 --> 00:02:33.083 Why would it be blurry? 00:02:33.297 --> 00:02:36.567 Well, you look down and that's the near part of the lens, 00:02:36.567 --> 00:02:39.275 but the next step was past arm's reach, 00:02:39.275 --> 00:02:41.104 which for your eyes, counts as far. 00:02:41.274 --> 00:02:44.143 The next solution I want to point out is a little less common 00:02:44.143 --> 00:02:46.757 but comes up a lot in contact lenses or LASIK surgeries, 00:02:46.757 --> 00:02:48.070 and it's called monovision. 00:02:48.070 --> 00:02:50.590 It works by setting up the dominant eye to focus far 00:02:50.590 --> 00:02:52.114 and the other eye to focus near. 00:02:52.114 --> 00:02:54.830 Your brain does the work of intelligently putting together 00:02:54.830 --> 00:02:56.816 the sharpest parts from each eye's view, 00:02:56.816 --> 00:02:59.004 but the two eyes see slightly different things, 00:02:59.004 --> 00:03:01.620 and that makes it harder to judge distances binocularly. 00:03:01.620 --> 00:03:03.150 So where does that all leave us? 00:03:03.150 --> 00:03:06.001 It seems like we've come up with a lot of different solutions 00:03:06.001 --> 00:03:08.338 but none of them quite restore natural refocusing. 00:03:08.338 --> 00:03:10.334 None of them let you just look at something 00:03:10.334 --> 00:03:11.738 and expect it to be in focus. 00:03:11.738 --> 00:03:12.736 But why? 00:03:12.840 --> 00:03:13.984 Well, to explain that 00:03:13.984 --> 00:03:16.693 we'll want to take a look at the anatomy of the human eye. 00:03:16.693 --> 00:03:19.877 The part of the eye that allows us to refocus to different distances 00:03:19.877 --> 00:03:21.398 is called the crystalline lens. 00:03:21.654 --> 00:03:25.644 There are muscles surrounding the lens that can deform it into different shapes, 00:03:25.644 --> 00:03:27.794 which in turn changes its focusing power. 00:03:27.794 --> 00:03:29.913 What happens when someone becomes presbyopic? 00:03:30.213 --> 00:03:32.399 It turns out that the crystalline lens stiffens 00:03:32.399 --> 00:03:35.078 to the point that it doesn't really change shape anymore. 00:03:35.078 --> 00:03:39.080 Now, thinking back on all the solutions I listed earlier, 00:03:39.080 --> 00:03:42.686 we can see that they all have something in common with the others 00:03:42.686 --> 00:03:44.311 but not with our eyes, 00:03:44.311 --> 00:03:46.204 and that is that they're all static. 00:03:46.290 --> 00:03:49.094 It's like the optical equivalent of a pirate with a peg leg. 00:03:49.094 --> 00:03:51.990 What is the optical equivalent of a modern prosthetic leg? 00:03:52.291 --> 00:03:55.524 The last several decades have seen the creation and rapid development 00:03:55.524 --> 00:03:57.927 of what are called "focus-tunable lenses." 00:03:58.333 --> 00:04:00.020 There are several different types. 00:04:00.020 --> 00:04:01.813 Mechanically-shifted Alvarez lenses, 00:04:01.813 --> 00:04:03.447 deformable liquid lenses 00:04:03.447 --> 00:04:05.875 and electronically-switched, liquid crystal lenses. 00:04:05.959 --> 00:04:07.686 Now these have their own trade-offs, 00:04:07.686 --> 00:04:10.287 but what they don't skimp on is the visual experience. 00:04:10.287 --> 00:04:13.618 Full, field-of-view vision that can be sharp at any desirable distance. 00:04:13.618 --> 00:04:14.619 OK, great. 00:04:14.619 --> 00:04:16.193 The lenses we need already exist. 00:04:16.193 --> 00:04:17.293 Problem solved, right? 00:04:17.786 --> 00:04:19.002 Not so fast. 00:04:19.156 --> 00:04:22.054 Focus-tunable lenses add a bit of complexity to the equation. 00:04:22.162 --> 00:04:25.981 The lenses don't have any way of knowing what distance they should be focused to. 00:04:25.981 --> 00:04:28.887 What we really need are glasses that, when you're looking far, 00:04:28.887 --> 00:04:30.001 far objects are sharp, 00:04:30.001 --> 00:04:31.153 and when you look near, 00:04:31.153 --> 00:04:33.924 near objects come into focus anywhere in your field of view 00:04:33.924 --> 00:04:35.908 and without you having to think about it. 00:04:35.908 --> 00:04:38.375 What I've worked on these last few years at Stanford 00:04:38.375 --> 00:04:40.914 is building that exact intelligence around the lenses. 00:04:40.914 --> 00:04:44.480 Our prototype borrows technology from virtual and augmented reality systems 00:04:44.480 --> 00:04:45.917 to estimate focusing distance. 00:04:45.917 --> 00:04:49.487 We have an eye tracker that can tell what direction our eyes are focused in. 00:04:49.487 --> 00:04:50.488 Using two of these, 00:04:50.488 --> 00:04:52.691 we can directly triangulate your gaze direction 00:04:52.691 --> 00:04:53.864 to get a focus estimate. 00:04:53.864 --> 00:04:54.864 Just in case though, 00:04:54.864 --> 00:04:57.483 to increase reliability we also added a distance sensor. 00:04:57.483 --> 00:04:59.820 The sensor is a camera that looks out at the world 00:04:59.820 --> 00:05:01.420 and reports distances to objects. 00:05:01.420 --> 00:05:04.420 We can again use your gaze direction to get a distance estimate 00:05:04.420 --> 00:05:05.599 for a second time. 00:05:05.599 --> 00:05:07.580 We then fuse those two distance estimates 00:05:07.580 --> 00:05:10.075 and update the focus-tunable lens power accordingly. 00:05:10.266 --> 00:05:13.592 The next step for us was of course to test our device on actual people. 00:05:13.592 --> 00:05:16.680 So we recruited about 100 presbyopes and had them test our device 00:05:16.680 --> 00:05:18.392 while we measured their performance. 00:05:18.392 --> 00:05:21.719 What we saw convinced us right then that autofocals were the future. 00:05:21.719 --> 00:05:23.634 Our participants could see more clearly, 00:05:23.634 --> 00:05:25.023 they could focus more quickly 00:05:25.023 --> 00:05:28.031 and they thought it was an easier and better focusing experience 00:05:28.031 --> 00:05:29.461 than their current correction. 00:05:29.461 --> 00:05:30.457 To put it simply, 00:05:30.457 --> 00:05:31.603 when it comes to vision, 00:05:31.603 --> 00:05:34.811 autofocals don't compromise like static corrections in use today do. 00:05:34.811 --> 00:05:36.758 But I don't want to get ahead of myself. 00:05:36.758 --> 00:05:39.500 There's a lot of work for my colleagues and me left to do. 00:05:39.500 --> 00:05:41.948 For example, our glasses are a bit -- 00:05:41.948 --> 00:05:42.947 (Laughter) 00:05:42.947 --> 00:05:44.462 bulky, maybe? 00:05:44.462 --> 00:05:47.698 And one reason for this is that we used bulkier components 00:05:47.698 --> 00:05:50.492 that are often intended for research use or industrial use. 00:05:50.492 --> 00:05:52.754 Another is that we need to strap everything down 00:05:52.754 --> 00:05:56.485 because current eye-tracking algorithms don't have the robustness that we need. 00:05:56.776 --> 00:05:58.051 So moving forward, 00:05:58.051 --> 00:06:00.556 as we move from a research setting into a start-up, 00:06:00.556 --> 00:06:02.618 we plan to make future autofocals 00:06:02.618 --> 00:06:05.171 eventually look a little bit more like normal glasses. 00:06:05.171 --> 00:06:06.168 For this to happen, 00:06:06.168 --> 00:06:08.554 we'll need to significantly improve 00:06:08.554 --> 00:06:10.667 the robustness of our eye-tracking solution. 00:06:10.667 --> 00:06:14.539 We'll also need to incorporate smaller and more efficient electronics and lenses. 00:06:14.919 --> 00:06:17.211 That said, even with our current prototype, 00:06:17.211 --> 00:06:19.762 we've shown that today's focus-tunable lens technology 00:06:19.762 --> 00:06:23.345 is capable of out-performing traditional forms of static correction. 00:06:23.345 --> 00:06:24.894 So it's only a matter of time. 00:06:25.134 --> 00:06:27.158 It's pretty clear that in the near future, 00:06:27.164 --> 00:06:30.168 instead of worrying about which pair of glasses to use and when, 00:06:30.168 --> 00:06:32.725 we'll be able to just focus on the important things. 00:06:33.687 --> 00:06:34.686 Thank you. 00:06:34.686 --> 00:06:36.438 (Applause)