1 00:00:00,875 --> 00:00:02,809 Every single one of us will lose 2 00:00:02,833 --> 00:00:06,684 or has already lost something we rely on every single day. 3 00:00:06,708 --> 00:00:09,518 I am of course talking about our keys. 4 00:00:09,542 --> 00:00:11,184 (Laughter) 5 00:00:11,208 --> 00:00:12,476 Just kidding. 6 00:00:12,500 --> 00:00:16,309 What I actually want to talk about is one of our most important senses: vision. 7 00:00:16,333 --> 00:00:19,143 Every single day we each lose a little bit of our ability 8 00:00:19,167 --> 00:00:20,476 to refocus our eyes 9 00:00:20,500 --> 00:00:22,809 until we can't refocus at all. 10 00:00:22,833 --> 00:00:24,809 We call this condition presbyopia, 11 00:00:24,833 --> 00:00:27,351 and it affects two billion people worldwide. 12 00:00:27,375 --> 00:00:29,518 That's right, I said billion. 13 00:00:29,542 --> 00:00:31,268 If you haven't heard of presbyopia, 14 00:00:31,292 --> 00:00:34,101 and you're wondering, "Where are these two billion people?" 15 00:00:34,125 --> 00:00:36,226 here's a hint before I get into the details. 16 00:00:36,250 --> 00:00:39,518 It's the reason why people wear reading glasses or bifocal lenses. 17 00:00:39,542 --> 00:00:42,400 I'll get started by describing the loss in refocusing ability 18 00:00:42,424 --> 00:00:43,934 leading up to presbyopia. 19 00:00:43,958 --> 00:00:46,184 As a newborn, you would have been able to focus 20 00:00:46,208 --> 00:00:48,351 as close as six and a half centimeters, 21 00:00:48,375 --> 00:00:49,643 if you wished to. 22 00:00:49,667 --> 00:00:52,809 By your mid-20s, you have about half of that focusing power left. 23 00:00:52,833 --> 00:00:54,101 10 centimeters or so, 24 00:00:54,125 --> 00:00:56,684 but close enough that you never notice the difference. 25 00:00:56,708 --> 00:00:57,976 By your late 40s though, 26 00:00:58,000 --> 00:01:00,351 the closest you can focus is about 25 centimeters, 27 00:01:00,375 --> 00:01:01,643 maybe even farther. 28 00:01:01,667 --> 00:01:03,768 Losses in focusing ability beyond this point 29 00:01:03,792 --> 00:01:06,018 start affecting near-vision tasks like reading, 30 00:01:06,042 --> 00:01:07,643 and by the time you reach age 60, 31 00:01:07,667 --> 00:01:10,018 nothing within a meter radius of you is clear. 32 00:01:10,042 --> 00:01:12,309 Right now some of you are probably thinking, 33 00:01:12,333 --> 00:01:15,643 that sounds bad but he means you in a figurative sense, 34 00:01:15,667 --> 00:01:19,101 only for the people that actually end up with presbyopia. 35 00:01:19,125 --> 00:01:23,559 But no, when I say you, I literally mean that every single one of you 36 00:01:23,583 --> 00:01:26,809 will someday be presbyopic if you aren't already. 37 00:01:26,833 --> 00:01:28,226 That sounds a bit troubling. 38 00:01:28,250 --> 00:01:31,934 I want to remind you that presbyopia has been with us for all of human history 39 00:01:31,958 --> 00:01:34,768 and we've done a lot of different things to try and fix it. 40 00:01:34,792 --> 00:01:38,684 So to start, let's imagine that you're sitting at a desk, reading. 41 00:01:38,708 --> 00:01:40,059 If you were presbyopic, 42 00:01:40,083 --> 00:01:42,143 it might look a little something like this. 43 00:01:42,167 --> 00:01:45,059 Anything close by, like the magazine, will be blurry. 44 00:01:45,083 --> 00:01:46,434 Moving on to solutions. 45 00:01:46,458 --> 00:01:48,101 First, reading glasses. 46 00:01:48,125 --> 00:01:50,184 These have lenses with a single focal power 47 00:01:50,208 --> 00:01:52,601 tuned so that near objects come into focus. 48 00:01:52,625 --> 00:01:55,226 But far objects necessarily go out of focus, 49 00:01:55,250 --> 00:01:57,726 meaning you have to constantly switch back and forth 50 00:01:57,750 --> 00:01:59,518 between wearing and not wearing them. 51 00:01:59,542 --> 00:02:00,809 To solve this problem 52 00:02:00,833 --> 00:02:04,101 Benjamin Franklin invented what he called "double spectacles." 53 00:02:04,125 --> 00:02:06,226 Today we call those bifocals, 54 00:02:06,250 --> 00:02:09,684 and what they let him do was see far when he looked up 55 00:02:09,708 --> 00:02:11,434 and see near when he looked down. 56 00:02:11,458 --> 00:02:14,434 Today we also have progressive lenses which get rid of the line 57 00:02:14,458 --> 00:02:17,059 by smoothly varying the focal power from top to bottom. 58 00:02:17,083 --> 00:02:18,518 The downside to both of these 59 00:02:18,542 --> 00:02:21,143 is that you lose field of vision at any given distance, 60 00:02:21,167 --> 00:02:23,768 because it gets split up from top to bottom like this. 61 00:02:23,792 --> 00:02:25,184 To see why that's a problem, 62 00:02:25,208 --> 00:02:28,059 imagine that you're climbing down a ladder or stairs. 63 00:02:28,083 --> 00:02:31,684 You look down to get your footing but it's blurry. 64 00:02:31,708 --> 00:02:33,101 Why would it be blurry? 65 00:02:33,125 --> 00:02:36,559 Well, you look down and that's the near part of the lens, 66 00:02:36,583 --> 00:02:39,143 but the next step was past arm's reach, 67 00:02:39,167 --> 00:02:41,268 which for your eyes counts as far. 68 00:02:41,292 --> 00:02:44,184 The next solution I want to point out is a little less common 69 00:02:44,208 --> 00:02:46,601 but comes up in contact lenses or LASIK surgeries, 70 00:02:46,625 --> 00:02:47,976 and it's called monovision. 71 00:02:48,000 --> 00:02:50,518 It works by setting up the dominant eye to focus far 72 00:02:50,542 --> 00:02:52,143 and the other eye to focus near. 73 00:02:52,167 --> 00:02:54,976 Your brain does the work of intelligently putting together 74 00:02:55,000 --> 00:02:56,976 the sharpest parts from each eye's view, 75 00:02:57,000 --> 00:02:59,268 but the two eyes see slightly different things, 76 00:02:59,292 --> 00:03:01,934 and that makes it harder to judge distances binocularly. 77 00:03:01,958 --> 00:03:03,351 So where does that leave us? 78 00:03:03,375 --> 00:03:05,226 We've come up with a lot of solutions 79 00:03:05,250 --> 00:03:07,851 but none of them quite restore natural refocusing. 80 00:03:07,875 --> 00:03:09,934 None of them let you just look at something 81 00:03:09,958 --> 00:03:11,434 and expect it to be in focus. 82 00:03:11,458 --> 00:03:12,809 But why? 83 00:03:12,833 --> 00:03:14,101 Well, to explain that 84 00:03:14,125 --> 00:03:16,851 we'll want to take a look at the anatomy of the human eye. 85 00:03:16,875 --> 00:03:20,101 The part of the eye that allows us to refocus to different distances 86 00:03:20,125 --> 00:03:21,684 is called the crystalline lens. 87 00:03:21,708 --> 00:03:25,559 There are muscles surrounding the lens that can deform it into different shapes, 88 00:03:25,583 --> 00:03:27,684 which in turn changes its focusing power. 89 00:03:27,708 --> 00:03:30,184 What happens when someone becomes presbyopic? 90 00:03:30,208 --> 00:03:32,434 It turns out that the crystalline lens stiffens 91 00:03:32,458 --> 00:03:35,143 to the point that it doesn't really change shape anymore. 92 00:03:35,167 --> 00:03:38,893 Now, thinking back on all the solutions I listed earlier, 93 00:03:38,917 --> 00:03:42,643 we can see that they all have something in common with the others 94 00:03:42,667 --> 00:03:44,143 but not with our eyes, 95 00:03:44,167 --> 00:03:46,184 and that is that they're all static. 96 00:03:46,208 --> 00:03:49,101 It's like the optical equivalent of a pirate with a peg leg. 97 00:03:49,125 --> 00:03:52,268 What is the optical equivalent of a modern prosthetic leg? 98 00:03:52,292 --> 00:03:55,559 The last several decades have seen the creation and rapid development 99 00:03:55,583 --> 00:03:58,268 of what are called "focus-tunable lenses." 100 00:03:58,292 --> 00:03:59,976 There are several different types. 101 00:04:00,000 --> 00:04:01,809 Mechanically-shifted Alvarez lenses, 102 00:04:01,833 --> 00:04:03,268 deformable liquid lenses 103 00:04:03,292 --> 00:04:05,851 and electronically-switched, liquid crystal lenses. 104 00:04:05,875 --> 00:04:07,684 Now these have their own trade-offs, 105 00:04:07,708 --> 00:04:10,309 but what they don't skimp on is the visual experience. 106 00:04:10,333 --> 00:04:13,601 Full-field-of-view vision that can be sharp at any desired distance. 107 00:04:13,625 --> 00:04:15,768 OK, great. The lenses we need already exist. 108 00:04:15,792 --> 00:04:17,684 Problem solved, right? 109 00:04:17,708 --> 00:04:19,143 Not so fast. 110 00:04:19,167 --> 00:04:22,143 Focus-tunable lenses add a bit of complexity to the equation. 111 00:04:22,167 --> 00:04:26,018 The lenses don't have any way of knowing what distance they should be focused to. 112 00:04:26,042 --> 00:04:27,351 What we need are glasses 113 00:04:27,375 --> 00:04:29,934 that, when you're looking far, far objects are sharp, 114 00:04:29,958 --> 00:04:31,268 and when you look near, 115 00:04:31,292 --> 00:04:33,726 near objects come into focus in your field of view, 116 00:04:33,750 --> 00:04:35,601 without you having to think about it. 117 00:04:35,625 --> 00:04:38,143 What I've worked on these last few years at Stanford 118 00:04:38,167 --> 00:04:40,768 is building that exact intelligence around the lenses. 119 00:04:40,792 --> 00:04:44,393 Our prototype borrows technology from virtual and augmented reality systems 120 00:04:44,417 --> 00:04:45,934 to estimate focusing distance. 121 00:04:45,958 --> 00:04:49,601 We have an eye tracker that can tell what direction our eyes are focused in. 122 00:04:49,625 --> 00:04:52,434 Using two of these, we can triangulate your gaze direction 123 00:04:52,458 --> 00:04:53,768 to get a focus estimate. 124 00:04:53,792 --> 00:04:55,976 Just in case though, to increase reliability, 125 00:04:56,000 --> 00:04:57,559 we also added a distance sensor. 126 00:04:57,583 --> 00:04:59,976 The sensor is a camera that looks out at the world 127 00:05:00,000 --> 00:05:01,601 and reports distances to objects. 128 00:05:01,625 --> 00:05:04,601 We can again use your gaze direction to get a distance estimate 129 00:05:04,625 --> 00:05:05,893 for a second time. 130 00:05:05,917 --> 00:05:07,893 We then fuse those two distance estimates 131 00:05:07,917 --> 00:05:10,393 and update the focus-tunable lens power accordingly. 132 00:05:10,417 --> 00:05:13,351 The next step for us was to test our device on actual people. 133 00:05:13,375 --> 00:05:16,518 So we recruited about 100 presbyopes and had them test our device 134 00:05:16,542 --> 00:05:18,351 while we measured their performance. 135 00:05:18,375 --> 00:05:21,643 What we saw convinced us right then that autofocals were the future. 136 00:05:21,667 --> 00:05:25,018 Our participants could see more clearly, they could focus more quickly 137 00:05:25,042 --> 00:05:28,059 and they thought it was an easier and better focusing experience 138 00:05:28,083 --> 00:05:29,559 than their current correction. 139 00:05:29,583 --> 00:05:31,643 To put it simply, when it comes to vision, 140 00:05:31,667 --> 00:05:34,893 autofocals don't compromise like static corrections in use today do. 141 00:05:34,917 --> 00:05:36,851 But I don't want to get ahead of myself. 142 00:05:36,875 --> 00:05:39,601 There's a lot of work for my colleagues and me left to do. 143 00:05:39,625 --> 00:05:41,893 For example, our glasses are a bit -- 144 00:05:41,917 --> 00:05:42,934 (Laughter) 145 00:05:42,958 --> 00:05:44,309 bulky, maybe? 146 00:05:44,333 --> 00:05:47,684 And one reason for this is that we used bulkier components 147 00:05:47,708 --> 00:05:50,518 that are often intended for research use or industrial use. 148 00:05:50,542 --> 00:05:52,809 Another is that we need to strap everything down 149 00:05:52,833 --> 00:05:56,643 because current eye-tracking algorithms don't have the robustness that we need. 150 00:05:56,667 --> 00:05:57,976 So moving forward, 151 00:05:58,000 --> 00:06:00,476 as we move from a research setting into a start-up, 152 00:06:00,500 --> 00:06:02,434 we plan to make future autofocals 153 00:06:02,458 --> 00:06:05,018 eventually look a little bit more like normal glasses. 154 00:06:05,042 --> 00:06:08,393 For this to happen, we'll need to significantly improve 155 00:06:08,417 --> 00:06:10,559 the robustness of our eye-tracking solution. 156 00:06:10,583 --> 00:06:14,768 We'll also need to incorporate smaller and more efficient electronics and lenses. 157 00:06:14,792 --> 00:06:16,976 That said, even with our current prototype, 158 00:06:17,000 --> 00:06:19,726 we've shown that today's focus-tunable lens technology 159 00:06:19,750 --> 00:06:23,309 is capable of outperforming traditional forms of static correction. 160 00:06:23,333 --> 00:06:24,976 So it's only a matter of time. 161 00:06:25,000 --> 00:06:27,059 It's pretty clear that in the near future, 162 00:06:27,083 --> 00:06:30,143 instead of worrying about which pair of glasses to use and when, 163 00:06:30,167 --> 00:06:32,708 we'll be able to just focus on the important things. 164 00:06:33,667 --> 00:06:34,934 Thank you. 165 00:06:34,958 --> 00:06:36,583 (Applause)