WEBVTT 00:00:00.875 --> 00:00:02.809 Every single one of us will lose 00:00:02.833 --> 00:00:06.684 or has already lost something we rely on every single day. 00:00:06.708 --> 00:00:09.518 I am of course talking about our keys. NOTE Paragraph 00:00:09.542 --> 00:00:11.184 (Laughter) NOTE Paragraph 00:00:11.208 --> 00:00:12.476 Just kidding. 00:00:12.500 --> 00:00:16.309 What I actually want to talk about is one of our most important senses: vision. 00:00:16.333 --> 00:00:19.143 Every single day we each lose a little bit of our ability 00:00:19.167 --> 00:00:20.476 to refocus our eyes 00:00:20.500 --> 00:00:22.809 until we can't refocus at all. 00:00:22.833 --> 00:00:24.809 We call this condition presbyopia, 00:00:24.833 --> 00:00:27.351 and it affects two billion people worldwide. 00:00:27.375 --> 00:00:29.518 That's right, I said billion. 00:00:29.542 --> 00:00:31.268 If you haven't heard of presbyopia, 00:00:31.292 --> 00:00:34.101 and you're wondering, "Where are these two billion people?" 00:00:34.125 --> 00:00:36.226 here's a hint before I get into the details. 00:00:36.250 --> 00:00:39.518 It's the reason why people wear reading glasses or bifocal lenses. NOTE Paragraph 00:00:39.542 --> 00:00:42.400 I'll get started by describing the loss in refocusing ability 00:00:42.424 --> 00:00:43.934 leading up to presbyopia. 00:00:43.958 --> 00:00:46.184 As a newborn, you would have been able to focus 00:00:46.208 --> 00:00:48.351 as close as six and a half centimeters, 00:00:48.375 --> 00:00:49.643 if you wished to. 00:00:49.667 --> 00:00:52.809 By your mid-20s, you have about half of that focusing power left. 00:00:52.833 --> 00:00:54.101 10 centimeters or so, 00:00:54.125 --> 00:00:56.684 but close enough that you never notice the difference. 00:00:56.708 --> 00:00:57.976 By your late 40s though, 00:00:58.000 --> 00:01:00.351 the closest you can focus is about 25 centimeters, 00:01:00.375 --> 00:01:01.643 maybe even farther. 00:01:01.667 --> 00:01:03.768 Losses in focusing ability beyond this point 00:01:03.792 --> 00:01:06.018 start affecting near-vision tasks like reading, 00:01:06.042 --> 00:01:07.643 and by the time you reach age 60, 00:01:07.667 --> 00:01:10.018 nothing within a meter radius of you is clear. NOTE Paragraph 00:01:10.042 --> 00:01:12.309 Right now some of you are probably thinking, 00:01:12.333 --> 00:01:15.643 that sounds bad but he means you in a figurative sense, 00:01:15.667 --> 00:01:19.101 only for the people that actually end up with presbyopia. 00:01:19.125 --> 00:01:23.559 But no, when I say you, I literally mean that every single one of you 00:01:23.583 --> 00:01:26.809 will someday be presbyopic if you aren't already. 00:01:26.833 --> 00:01:28.226 That sounds a bit troubling. 00:01:28.250 --> 00:01:31.934 I want to remind you that presbyopia has been with us for all of human history 00:01:31.958 --> 00:01:34.768 and we've done a lot of different things to try and fix it. 00:01:34.792 --> 00:01:38.684 So to start, let's imagine that you're sitting at a desk, reading. 00:01:38.708 --> 00:01:40.059 If you were presbyopic, 00:01:40.083 --> 00:01:42.143 it might look a little something like this. 00:01:42.167 --> 00:01:45.059 Anything close by, like the magazine, will be blurry. 00:01:45.083 --> 00:01:46.434 Moving on to solutions. 00:01:46.458 --> 00:01:48.101 First, reading glasses. 00:01:48.125 --> 00:01:50.184 These have lenses with a single focal power 00:01:50.208 --> 00:01:52.601 tuned so that near objects come into focus. 00:01:52.625 --> 00:01:55.226 But far objects necessarily go out of focus, 00:01:55.250 --> 00:01:57.726 meaning you have to constantly switch back and forth 00:01:57.750 --> 00:01:59.518 between wearing and not wearing them. 00:01:59.542 --> 00:02:00.809 To solve this problem 00:02:00.833 --> 00:02:04.101 Benjamin Franklin invented what he called "double spectacles." 00:02:04.125 --> 00:02:06.226 Today we call those bifocals, 00:02:06.250 --> 00:02:09.684 and what they let him do was see far when he looked up 00:02:09.708 --> 00:02:11.434 and see near when he looked down. 00:02:11.458 --> 00:02:14.434 Today we also have progressive lenses which get rid of the line 00:02:14.458 --> 00:02:17.059 by smoothly varying the focal power from top to bottom. 00:02:17.083 --> 00:02:18.518 The downside to both of these 00:02:18.542 --> 00:02:21.143 is that you lose field of vision at any given distance, 00:02:21.167 --> 00:02:23.768 because it gets split up from top to bottom like this. 00:02:23.792 --> 00:02:25.184 To see why that's a problem, 00:02:25.208 --> 00:02:28.059 imagine that you're climbing down a ladder or stairs. 00:02:28.083 --> 00:02:31.684 You look down to get your footing but it's blurry. 00:02:31.708 --> 00:02:33.101 Why would it be blurry? 00:02:33.125 --> 00:02:36.559 Well, you look down and that's the near part of the lens, 00:02:36.583 --> 00:02:39.143 but the next step was past arm's reach, 00:02:39.167 --> 00:02:41.268 which for your eyes counts as far. NOTE Paragraph 00:02:41.292 --> 00:02:44.184 The next solution I want to point out is a little less common 00:02:44.208 --> 00:02:46.601 but comes up in contact lenses or LASIK surgeries, 00:02:46.625 --> 00:02:47.976 and it's called monovision. 00:02:48.000 --> 00:02:50.518 It works by setting up the dominant eye to focus far 00:02:50.542 --> 00:02:52.143 and the other eye to focus near. 00:02:52.167 --> 00:02:54.976 Your brain does the work of intelligently putting together 00:02:55.000 --> 00:02:56.976 the sharpest parts from each eye's view, 00:02:57.000 --> 00:02:59.268 but the two eyes see slightly different things, 00:02:59.292 --> 00:03:01.934 and that makes it harder to judge distances binocularly. NOTE Paragraph 00:03:01.958 --> 00:03:03.351 So where does that leave us? 00:03:03.375 --> 00:03:05.226 We've come up with a lot of solutions 00:03:05.250 --> 00:03:07.851 but none of them quite restore natural refocusing. 00:03:07.875 --> 00:03:09.934 None of them let you just look at something 00:03:09.958 --> 00:03:11.434 and expect it to be in focus. NOTE Paragraph 00:03:11.458 --> 00:03:12.809 But why? 00:03:12.833 --> 00:03:14.101 Well, to explain that 00:03:14.125 --> 00:03:16.851 we'll want to take a look at the anatomy of the human eye. 00:03:16.875 --> 00:03:20.101 The part of the eye that allows us to refocus to different distances 00:03:20.125 --> 00:03:21.684 is called the crystalline lens. 00:03:21.708 --> 00:03:25.559 There are muscles surrounding the lens that can deform it into different shapes, 00:03:25.583 --> 00:03:27.684 which in turn changes its focusing power. 00:03:27.708 --> 00:03:30.184 What happens when someone becomes presbyopic? 00:03:30.208 --> 00:03:32.434 It turns out that the crystalline lens stiffens 00:03:32.458 --> 00:03:35.143 to the point that it doesn't really change shape anymore. NOTE Paragraph 00:03:35.167 --> 00:03:38.893 Now, thinking back on all the solutions I listed earlier, 00:03:38.917 --> 00:03:42.643 we can see that they all have something in common with the others 00:03:42.667 --> 00:03:44.143 but not with our eyes, 00:03:44.167 --> 00:03:46.184 and that is that they're all static. 00:03:46.208 --> 00:03:49.101 It's like the optical equivalent of a pirate with a peg leg. 00:03:49.125 --> 00:03:52.268 What is the optical equivalent of a modern prosthetic leg? NOTE Paragraph 00:03:52.292 --> 00:03:55.559 The last several decades have seen the creation and rapid development 00:03:55.583 --> 00:03:58.268 of what are called "focus-tunable lenses." 00:03:58.292 --> 00:03:59.976 There are several different types. 00:04:00.000 --> 00:04:01.809 Mechanically-shifted Alvarez lenses, 00:04:01.833 --> 00:04:03.268 deformable liquid lenses 00:04:03.292 --> 00:04:05.851 and electronically-switched, liquid crystal lenses. 00:04:05.875 --> 00:04:07.684 Now these have their own trade-offs, 00:04:07.708 --> 00:04:10.309 but what they don't skimp on is the visual experience. 00:04:10.333 --> 00:04:13.601 Full-field-of-view vision that can be sharp at any desired distance. NOTE Paragraph 00:04:13.625 --> 00:04:15.768 OK, great. The lenses we need already exist. 00:04:15.792 --> 00:04:17.684 Problem solved, right? 00:04:17.708 --> 00:04:19.143 Not so fast. 00:04:19.167 --> 00:04:22.143 Focus-tunable lenses add a bit of complexity to the equation. 00:04:22.167 --> 00:04:26.018 The lenses don't have any way of knowing what distance they should be focused to. 00:04:26.042 --> 00:04:27.351 What we need are glasses 00:04:27.375 --> 00:04:29.934 that, when you're looking far, far objects are sharp, 00:04:29.958 --> 00:04:31.268 and when you look near, 00:04:31.292 --> 00:04:33.726 near objects come into focus in your field of view, 00:04:33.750 --> 00:04:35.601 without you having to think about it. NOTE Paragraph 00:04:35.625 --> 00:04:38.143 What I've worked on these last few years at Stanford 00:04:38.167 --> 00:04:40.768 is building that exact intelligence around the lenses. 00:04:40.792 --> 00:04:44.393 Our prototype borrows technology from virtual and augmented reality systems 00:04:44.417 --> 00:04:45.934 to estimate focusing distance. 00:04:45.958 --> 00:04:49.601 We have an eye tracker that can tell what direction our eyes are focused in. 00:04:49.625 --> 00:04:52.434 Using two of these, we can triangulate your gaze direction 00:04:52.458 --> 00:04:53.768 to get a focus estimate. 00:04:53.792 --> 00:04:55.976 Just in case though, to increase reliability, 00:04:56.000 --> 00:04:57.559 we also added a distance sensor. 00:04:57.583 --> 00:04:59.976 The sensor is a camera that looks out at the world 00:05:00.000 --> 00:05:01.601 and reports distances to objects. 00:05:01.625 --> 00:05:04.601 We can again use your gaze direction to get a distance estimate 00:05:04.625 --> 00:05:05.893 for a second time. 00:05:05.917 --> 00:05:07.893 We then fuse those two distance estimates 00:05:07.917 --> 00:05:10.393 and update the focus-tunable lens power accordingly. NOTE Paragraph 00:05:10.417 --> 00:05:13.351 The next step for us was to test our device on actual people. 00:05:13.375 --> 00:05:16.518 So we recruited about 100 presbyopes and had them test our device 00:05:16.542 --> 00:05:18.351 while we measured their performance. 00:05:18.375 --> 00:05:21.643 What we saw convinced us right then that autofocals were the future. 00:05:21.667 --> 00:05:25.018 Our participants could see more clearly, they could focus more quickly 00:05:25.042 --> 00:05:28.059 and they thought it was an easier and better focusing experience 00:05:28.083 --> 00:05:29.559 than their current correction. 00:05:29.583 --> 00:05:31.643 To put it simply, when it comes to vision, 00:05:31.667 --> 00:05:34.893 autofocals don't compromise like static corrections in use today do. NOTE Paragraph 00:05:34.917 --> 00:05:36.851 But I don't want to get ahead of myself. 00:05:36.875 --> 00:05:39.601 There's a lot of work for my colleagues and me left to do. 00:05:39.625 --> 00:05:41.893 For example, our glasses are a bit -- NOTE Paragraph 00:05:41.917 --> 00:05:42.934 (Laughter) NOTE Paragraph 00:05:42.958 --> 00:05:44.309 bulky, maybe? 00:05:44.333 --> 00:05:47.684 And one reason for this is that we used bulkier components 00:05:47.708 --> 00:05:50.518 that are often intended for research use or industrial use. 00:05:50.542 --> 00:05:52.809 Another is that we need to strap everything down 00:05:52.833 --> 00:05:56.643 because current eye-tracking algorithms don't have the robustness that we need. 00:05:56.667 --> 00:05:57.976 So moving forward, 00:05:58.000 --> 00:06:00.476 as we move from a research setting into a start-up, 00:06:00.500 --> 00:06:02.434 we plan to make future autofocals 00:06:02.458 --> 00:06:05.018 eventually look a little bit more like normal glasses. 00:06:05.042 --> 00:06:08.393 For this to happen, we'll need to significantly improve 00:06:08.417 --> 00:06:10.559 the robustness of our eye-tracking solution. 00:06:10.583 --> 00:06:14.768 We'll also need to incorporate smaller and more efficient electronics and lenses. 00:06:14.792 --> 00:06:16.976 That said, even with our current prototype, 00:06:17.000 --> 00:06:19.726 we've shown that today's focus-tunable lens technology 00:06:19.750 --> 00:06:23.309 is capable of outperforming traditional forms of static correction. 00:06:23.333 --> 00:06:24.976 So it's only a matter of time. NOTE Paragraph 00:06:25.000 --> 00:06:27.059 It's pretty clear that in the near future, 00:06:27.083 --> 00:06:30.143 instead of worrying about which pair of glasses to use and when, 00:06:30.167 --> 00:06:32.708 we'll be able to just focus on the important things. NOTE Paragraph 00:06:33.667 --> 00:06:34.934 Thank you. NOTE Paragraph 00:06:34.958 --> 00:06:36.583 (Applause)