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    Everybody welcome to another episode
    The Anxious Resistance.
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    Today, I'm going to be talking about
    Effexor, also known by its generic name
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    "Venlafaxine".
    Effexor is an antidepressant SNRI class.
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    It's been used to treat
    multiple conditions. Such as major
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    depressive disorder, generalized anxiety,
    disorder, panic disorder,
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    social anxiety disorder, chronic pain,
    and hot flashes.
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    In 2020 was the 43rd most prescribed
    medication in the United States,
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    with 15 million prescriptions.
    This is a very commonly used medication.
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    Let's talk a little bit,
    about the history of Effexor.
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    Effexor was approved for use
    in the United States in 1993
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    I'ts been around for 30 years now.
    How does Effexor work?
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    Effexor, or Venlafaxine is a serotonin
    norepinephrine reuptake inhibitor
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    It's selectively inhibits
    the reuptake of both norepinephrine, and
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    serotonin. This increases
    the levels of these neurotransmitters
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    in a synaptic cleft. The higher
    levels of these neurotransmitters
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    are linked to better mood, and less
    less depressions.
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    What kind of side effects are there
    when taking Effexor?
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    Side effects may include, but
    are not limted to this list
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    Asthenia, headache, somnolence, dizziness,
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    nervousness, insomnia, anxiety, tremor,
    abnormal dreams, paresthesia,
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    agitation, weakness, syncope,
    taste alteration, apathy, confusion,
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    hypertension, hypotension, tachycardia.
    Okay, there's a lot y'all.
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    There are a lot of side effects to
    this medication. Now, a lot
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    of these can be only
    experienced at really high doses, a lot.
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    of these you may get initially, and then
    will go away. So really there's a lot
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    of side effects. It´s like one of
    those medications,
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    where they just babble on gibberish for
    like five minutes.
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    of side effects. Chances of you
    getting most of these
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    are very slim. There´s a few
    that maybe you´ll
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    get. Maybe you´ll get some dizziness,
    maybe you´ll get some
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    tiredness. Definitely with
    all these kind
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    of SSRI, SNRI medications you may
    have difficulty with your
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    libido. You may have difficulty
    reaching orgasm
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    that kind of things. You need to be
    aware of a couple specific,
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    like dangerous things, when it comes
    to these medications.
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    The first being serotonin syndrome,
    drugs that work on.
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    serotonin like venlafaxine,
    increase someone's risk
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    of developing serotonin syndrome,
    this occurs where there's
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    too much serotonin,
    and the symptoms include:
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    a high heart rate, sweating, headache,
    agitation, restlessness, anxiety,
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    goosebumps and rigid muscles.
    There are some severe symptoms
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    if this gets
    really bad too
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    which includes: a high fever,
    seizures, irregular heart rhythm,
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    and loss of consciousness.
    If you suspect
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    that you're having serotonin syndrome,
    you should go to the hospital,
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    or be checked out by your provider.
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    Again, you should especially
    be careful of
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    serotonin syndrome if you're on
    multiple medications
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    that increase levels of
    serotonin like other SSRI, SNRI
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    medications, buspirone, hydroxyzine,
    other antidrepressants,
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    antipsychotics, there's quite
    a few, be careful.
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    But again, this is an effective
    medication and
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    It's been used for a long time
    to treat anxiety,
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    to treat depression,
    to treat those conditions
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    I mentioned before. Don't
    be dissuased by the possible
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    side effects, these are
    possible not guaranteed
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    Also with Effexor, there's also a bit
    of a withdrawal syndrome
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    antidrepressant medications like
    venlafaxine, need to be
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    tapered off in order to
    avoid or mitigate withdrawal
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    symptoms of withdrawal include:
    dizziness, aches, chills
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    and headaches, you need to come off
    of this slowly if you're
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    coming off of it, especially if
    you've been here for a while
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    and especially if you're
    at a high dose.
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    What are some positivies of venlafaxine?
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    you've heard some negativies,
    some side effects,
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    again, if your doctor and
    you patient it may be
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    way worth it, to put up with
    some of this side effects
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    which likely you won't
    experience many
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    you'll experience maybe a few, and a lot
    of them will obey over time
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    positivies or pros of venlafaxine;
    Is a very effective medication
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    for anxiety and depression.
    And it's been around for several decades
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    It's very well
    researched, and can be
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    used to great effects.
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    What are some negatives or
    cons of Venlafaxine?
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    Like other antidepressants it can
    cause sexual dysfunction.
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    It can also make suicidal ideation
    or depression worse
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    and this is more likely in young
    adults and children.
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    Overall, What´s our take on
    Venlafaxine use?
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    venlafaxine is a well established
    treatment for anxiety
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    and depression as well as
    several other conditions
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    and it is considered a second-line
    treatment. Usually you
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    go to the SSRIs first and then
    you go to SNRIs. Effexor,
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    Prestique, Cymbalta, there's a.
    Couple others out
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    There depending on what country
    you live in. Good
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    medication
    If you enjoyed this video, If you.
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    learned something about Effexor
    or Venlafaxine, please
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    like the video, subscribe to our channel
    If you want more information
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    about any kind of mental health
    treatment and things that
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    can do to improve your life, and
    help you feel better and
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    overcome your mental health condition.
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    Thank you so much for watching.
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Video Language:
Italian
Duration:
05:29

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